DEPLETION OF BODY POTASSIUM BY DIURETICS

Depletion of body potassium by diuretics.

THE occurrence of ulcers in the small intestine during the course of treatment of patients with thiazide diuretics together with enteric-coated tablets of potassium chloride or enteric-coated tablets of combinations of thiazides and potassium chloride has suggested to several investigators that some factor in these medications may be responsible for the genesis of such ulcers.1' 2 As a matter o...

Diuretics, potassium, and ventricular ectopy.

I tion alone accounted for this and whether the reduction would have been greater had the diuretics not caused a ‘‘backlash’’ of cardiotoxicty. Certainly, the introduction of orally available thiazide diuretics in 1957–8 revn November 1985, we reviewed the then current status of experimental and clinical evidence and opinion on diuretic-associated hypokalemia with particular attention to its po...

Potassium-Sparing Diuretics in Hypertension

Renal mechanisms of potassium depletion

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Potassium depletion in heart failure and its relation to long-term treatment with diuretics: a review of the literature.

There have been many studies which suggest that patients with heart failure were potassium depleted. This depletion has been attributed to the use of potent diuretics, and these are now given with either potassium supplements or potassium-retaining diuretics. A detailed examination of the studies suggests that the reported decrease in body potassium compared with the results in healthy persons ...